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Cat No. | Product Name | Synonyms | Targets |
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T5144 | Desmopressin acetate (16679-58-6 free base) | Desmopressin acetate,DDAVP | Vasopressin Receptor |
Desmopressin acetate (16679-58-6 free base) (DDAVP) is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyur... | |||
T79188 | BT100 | Integrin | |
BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1]. | |||
T78666 | Egaptivon pegol | ARC 1779 | Integrin |
Egaptivon pegol (ARC1779) is an aptamer that inhibits the interaction of von Willebrand Factor (VWF) with platelet GPIb receptors, exhibiting anti-thrombotic efficacy. | |||
T78283 | Caplacizumab | ALX-0081,ALX-0681 | |
Caplacizumab (ALX-0681), a humanized anti-von Willebrand factor (vWF) nanobody, serves to impede vWF-mediated platelet adhesion, thereby averting additional microthrombi formation. This compound is utilized in the study ... | |||
T36221 | 2-chloro Palmitic Acid | ||
2-chloro Palmitic acid is a monochlorinated form of palmitic acid . It is produced in a myeloperoxidase (MPO) and time-dependent manner in neutrophils stimulated by phorbol 12-myristate 13-acetate . 2-chloro Palmitic aci... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01075 | Von Willebrand Factor/vWF Protein, Human, Recombinant (His) | Human | CHO |
Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vasc... | |||
TMPH-02974 | Von Willebrand Factor/vWF Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GP... | |||
TMPY-01755 | VWC2 Protein, Human, Recombinant (His) | Human | HEK293 |
Brorin, also known as brain-specific chordin-like protein, von Willebrand factor C domain-containing protein 2 and VWC2, is a secreted protein that contains two VWFC domains. VWC2 / Brorin is a BMP antagonist that may pl... | |||
TMPH-02484 | ADAMTS13 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation. | |||
TMPY-05716 | Integrin alpha V beta 3 Protein, Human, Recombinant (His) | Human | HEK293 |
Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. | |||
TMPH-00216 | SVMP Protein, Bothrops jararaca, Recombinant (His & KSI) | Bothrops jararaca | E. coli |
Metalloproteinase that binds to von Willebrand factor (VWF) and induces its interaction with GPIb (GP1BA), resulting in platelet aggregation. | |||
TMPY-03234 | CD42c Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Platelet glycoprotein Ib (GPIb) complex is best known as a major platelet receptor for von Willebrand factor essential for platelet adhesion under high shear conditions found in arteries and thrombosis. The GPIb complex ... | |||
TMPY-01218 | CD42c Protein, Human, Recombinant (His) | Human | HEK293 |
Platelet glycoprotein Ib (GPIb) complex is best known as a major platelet receptor for von Willebrand factor essential for platelet adhesion under high shear conditions found in arteries and thrombosis. The GPIb complex ... | |||
TMPH-01870 | Plasminogen Protein, Human, Recombinant (His) | Human | E. coli |
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the... | |||
TMPJ-01177 | NOV/CCN3 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor... | |||
TMPY-00950 | WISP1/CCN4 Protein, Human, Recombinant (His) | Human | HEK293 |
CCN4/Wnt-induced secreted protein 1 (WISP1) is a secreted, cysteine-rich, heparin-binding glycoprotein, belonging to the CCN (CTGF/CYR61/NOV) family of growth factors, and is involved in diverse biological functions such... |